Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

Study Counts

Type Study_count
Total_Studies 138
interventional 105
Observational 30
Registry 3

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Device 38
Drug 26
Drug|placebo 17
Other 6
Procedure 5
Drug|Procedure 3
Radiation 3
Behavioral 2
Device|Other 2
Diagnostic Test 1
Drug|Other 1
Other|placebo 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 60
France 10
Canada 6
NA 6
Korea, Republic of 3
Italy 2
Australia 1
Belgium 1
Canada|Korea, Republic of 1
China 1
China|Japan|Taiwan 1
Germany 1
Iran, Islamic Republic of 1
Lebanon 1
Norway 1
Spain 1
Spain|United Kingdom 1
Sweden 1
Switzerland 1
Taiwan 1
United Kingdom 1
United States|Austria|France|Germany|Spain|United Kingdom 1
United States|Canada 1
United States|Canada|Japan|Korea, Republic of 1

Sites per Study

Site_count Study_Count
1 79
2 10
3 2
4 2
6 2
7 2
8 2
10 2
11 1
17 1
22 1
26 1

Phase

Phase Study_Count
N/A 59
Phase 2 21
Phase 4 8
Phase 3 7
Phase 1 5
Phase 1/Phase 2 4
Phase 2/Phase 3 1

Number of Arms

Number_of_Arms Count_of_Studies
1 38
2 55
3 2
NA 10

Enrollment Metrics by Phase

Measure N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 6.00000 10.0 10.0 6.00000 175 30.00000 7.000
1st Qu. 15.00000 12.0 14.5 19.00000 175 52.50000 14.500
Median 23.00000 15.0 16.5 25.00000 175 79.00000 19.000
Mean 45.77586 19.4 18.0 30.33333 175 95.83333 28.125
3rd Qu. 43.00000 18.0 20.0 33.00000 175 110.00000 26.000
Max. 263.00000 42.0 29.0 95.00000 175 223.00000 100.000

Trial Group Type

group_type Group_Count
Experimental 93
Active Comparator 21
Placebo Comparator 18
NA 10
Other 9
Sham Comparator 7
No Intervention 6

Intervention Model

intervention_model Study_Count
Single Group Assignment 44
Crossover Assignment 29
Parallel Assignment 27
NA 5

Primary Purpose

primary_purpose Study_Count
Treatment 81
Basic Science 8
Diagnostic 6
Other 4
Device Feasibility 2
Supportive Care 2
NA 2

Observational Studies

Studies by Country

Country Study_Count
United States 20
NA 3
France 2
China 1
India 1
Israel 1
United States|Germany 1
United States|Germany|Taiwan 1

Sites per Study

Site_count Study_Count
1 25
2 2
5 1
7 1
9 1

Enrollment Metrics

Measure Observational
Min 2.0000
1st Qu 20.7500
Median 52.0000
Mean 204.4667
3rd Qu 190.5000
Max 1000.0000

Observation Model

observational_model Study_Count
Cohort 11
Case-Control 6
Case-Only 6
Other 3
Case Control 2
NA 2

Time Perspective

time_perspective Study_Count
Prospective 16
Cross-Sectional 7
Retrospective 4
NA 2
Other 1

Registries

Studies by Country

Country Study_Count
United States 2
United States|Canada|Israel 1

Sites per Study

Site_count Study_Count
1 2
8 1

Enrollment Metrics

Measure Registries
Min 500.0000
1st Qu 500.0000
Median 500.0000
Mean 666.6667
3rd Qu 750.0000
Max 1000.0000

Registry Model

observational_model Study_Count
Case-Control 1
Cohort 1
Other 1

Time Perspective

time_perspective Study_Count
Prospective 2
Cross-Sectional 1

Follow-up

target_duration Study_Count
1 Day 1
3 Years 1
5 Years 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT02947841 The Effectiveness of Alternating Stimulation in Preventing Tolerance in Essential Tremor Patients https://ClinicalTrials.gov/show/NCT02947841 Completed Oregon Health and Science University 2017-06-30
NCT01864525 Effects of Octanoic Acid for Treatment of Essential Voice Tremor https://ClinicalTrials.gov/show/NCT01864525 Completed Syracuse University 2016-12-22
NCT04112381 Bilateral Treatment of Medication Refractory Essential Tremor https://ClinicalTrials.gov/show/NCT04112381 Recruiting InSightec 2022-03-31
NCT02289560 Continued Access Protocol: ExAblate Transcranial MR Guided Focused Ultrasound for the Treatment of Essential Tremors https://ClinicalTrials.gov/show/NCT02289560 Active, not recruiting InSightec 2020-12-31
NCT02384343 Intravenous Dexmedetomidine for Treatment of Shivering During Cesarean Section Under Neuraxial Anesthesia https://ClinicalTrials.gov/show/NCT02384343 Completed St. Justine’s Hospital 2016-05-31
NCT03337334 Effects of High Amplitude and Focused tACS on Entraining Physiological Tremor https://ClinicalTrials.gov/show/NCT03337334 Completed KU Leuven 2017-04-30
NCT03305588 RAD 1601: EDGE Radiosurgery for Intractable Essential Tremor and Tremor-Dominant Parkinson’s Disease https://ClinicalTrials.gov/show/NCT03305588 Recruiting University of Alabama at Birmingham 2021-11-30
NCT03301272 Effectiveness of Botox on Reducing Rest Tremor in Parkinson’s Disease https://ClinicalTrials.gov/show/NCT03301272 Completed University of North Carolina, Chapel Hill 2019-08-21
NCT03292458 Sodium Oxybate in Spasmodic Dysphonia and Voice Tremor https://ClinicalTrials.gov/show/NCT03292458 Recruiting Massachusetts Eye and Ear Infirmary 2022-08-31
NCT03253991 A Study to Evaluate the Effectiveness and Safety of ExAblate MRgFUS on Essential Tremor https://ClinicalTrials.gov/show/NCT03253991 Recruiting InSightec 2023-01-01
NCT03156517 A Controlled Comparison of Two DBS Targets for Upper Extremity Action Tremor https://ClinicalTrials.gov/show/NCT03156517 Enrolling by invitation Oslo University Hospital 2020-04-30
NCT03136341 A Cross Over Pilot Study of Abobotulinum Toxin A (Dysport) as a Treatment for Task-dependent Upper Limb Tremor https://ClinicalTrials.gov/show/NCT03136341 Active, not recruiting Icahn School of Medicine at Mount Sinai 2022-12-31
NCT03074422 Effectiveness and Reliability of Hypnosis in Stereotaxy https://ClinicalTrials.gov/show/NCT03074422 Recruiting University Hospital, Geneva 2019-07-30
NCT03051178 Wearable Sensor for Responsive DBS for ET https://ClinicalTrials.gov/show/NCT03051178 Recruiting University of Florida 2020-12-01
NCT02978781 A Study to Evaluate SAGE-217 in Subjects With Essential Tremor https://ClinicalTrials.gov/show/NCT02978781 Completed Sage Therapeutics 2017-11-22
NCT02909907 Comparison of Botulinum Toxin Injections in Forearm FLexor Plus EXtensor Muscles vs. Flexor Muscles Alone for Treatment of Essential Hand Tremor(FLEX-D ET) https://ClinicalTrials.gov/show/NCT02909907 Completed The Cleveland Clinic 2018-02-28
NCT02883738 Evaluation the Effect of Muscle Functional Electrical Stimulation in the Upper Limb Tremor Invalidating https://ClinicalTrials.gov/show/NCT02883738 Completed University Hospital, Montpellier 2013-12-31
NCT02818777 A Study of Tolerability and Efficacy of Cannabidiol on Tremor in Parkinson’s Disease https://ClinicalTrials.gov/show/NCT02818777 Completed University of Colorado, Denver 2017-11-30
NCT02763865 A Pilot Study to Assess the Effects of Pre-SMA LF-rTMS for the Treatment of Essential Tremor https://ClinicalTrials.gov/show/NCT02763865 Completed Medical University of South Carolina 2015-12-31
NCT02704793 Cerebellar rTMS for Essential Tremor https://ClinicalTrials.gov/show/NCT02704793 Completed Mashhad University of Medical Sciences 2018-05-31
NCT02678429 Atlas Predicted DBS Settings in Essential Tremor https://ClinicalTrials.gov/show/NCT02678429 Completed Vanderbilt University Medical Center 2019-12-31
NCT02649166 Responsive Deep Brain Stimulator for Essential Tremor https://ClinicalTrials.gov/show/NCT02649166 Recruiting University of Florida 2021-11-30
NCT02629614 Cala ONE Device for Essential Tremor https://ClinicalTrials.gov/show/NCT02629614 Completed Cala Health, Inc. 2016-11-30
NCT02603926 Treatment of Fragile-X Associated Tremor/Ataxia Syndrome (FXTAS) With Allopregnanolone https://ClinicalTrials.gov/show/NCT02603926 Completed University of California, Davis 2016-12-31
NCT02585583 Deep Brain Frameless Radiosurgery for Drug Resistant Invalidating Tremor. Dose Escalation Pilot Study https://ClinicalTrials.gov/show/NCT02585583 Recruiting Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta 2021-12-31
NCT01581580 Deep Brain Stimulation Surgery for Movement Disorders https://ClinicalTrials.gov/show/NCT01581580 Recruiting National Institutes of Health Clinical Center (CC) 2021-10-01
NCT02553525 Effects of Stimulation Patterns of Deep Brain Stimulation https://ClinicalTrials.gov/show/NCT02553525 Enrolling by invitation Duke University 2022-08-31
NCT02555982 Evaluation of Botulinum Toxin Injection Efficacy in the Treatment of Head Essential Tremor https://ClinicalTrials.gov/show/NCT02555982 Recruiting University Hospital, Clermont-Ferrand 2020-09-30
NCT02551848 Kinematic-based BoNT-A Injections for Bilateral ET https://ClinicalTrials.gov/show/NCT02551848 Active, not recruiting Western University, Canada 2020-09-30
NCT02495883 Functional Imaging of Tremor Circuits and Mechanisms of Treatment Response https://ClinicalTrials.gov/show/NCT02495883 Active, not recruiting University of California, San Diego 2019-12-31
NCT02491554 Deep braIn Stimulation for Tremor TractographIC Versus Traditional https://ClinicalTrials.gov/show/NCT02491554 Recruiting University Hospital Freiburg 2020-02-28
NCT02466191 Treatment of Pendular Nystagmus in OPT https://ClinicalTrials.gov/show/NCT02466191 Completed Hospices Civils de Lyon 2016-01-31
NCT02441985 rTMS Therapy for Primary Orthostatic Tremor https://ClinicalTrials.gov/show/NCT02441985 Completed University of Florida 2019-01-08
NCT02427646 Kinematic-guided BoNT-A Treatment for ET and PD Tremor https://ClinicalTrials.gov/show/NCT02427646 Active, not recruiting Western University, Canada 2015-04-30
NCT02419313 Investigation of the Efficacy and Safety of IncobotulinumtoxinA (Xeomin) in Parkinson’s Tremor: A Customized Approach https://ClinicalTrials.gov/show/NCT02419313 Completed Yale University 2015-09-30
NCT02334683 Compare Two Guidance Techniques for Botulinum Toxin Injections for the Treatment of Limb Spasticity and Focal Dystonia https://ClinicalTrials.gov/show/NCT02334683 Recruiting Icahn School of Medicine at Mount Sinai 2020-08-31
NCT02277106 Evaluate SAGE-547 in Patients With Essential Tremor https://ClinicalTrials.gov/show/NCT02277106 Completed Sage Therapeutics 2015-08-31
NCT02264925 Thalamic LFPs and VIM DBS in Essential Tremor: Correlation, Evolution, and Therapeutic Perspectives https://ClinicalTrials.gov/show/NCT02264925 Active, not recruiting University Hospital, Bordeaux 2019-09-30
NCT02255929 Gamma Knife Radiosurgery for Treatment of Essential Tremor https://ClinicalTrials.gov/show/NCT02255929 Active, not recruiting Swedish Medical Center 2021-12-31
NCT02252380 ExAblate Transcranial MRgFUS for the Management of Treatment-Refractory Movement Disorders https://ClinicalTrials.gov/show/NCT02252380 Active, not recruiting InSightec 2021-12-31
NCT02207946 Botulinum Toxin A to Treat Arm Tremor https://ClinicalTrials.gov/show/NCT02207946 Completed Merz Pharmaceuticals GmbH 2016-05-31
NCT02197104 Citocoline for Treatment of FXTAS https://ClinicalTrials.gov/show/NCT02197104 Completed Rush University Medical Center 2017-01-31
NCT02111369 Propranolol and Botulinum Toxin for Essential Vocal Tremor https://ClinicalTrials.gov/show/NCT02111369 Completed Emory University 2014-10-31
NCT02095600 Radiosurgery for Drug Resistant Invalidating Tremor https://ClinicalTrials.gov/show/NCT02095600 Completed Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta 2016-12-31
NCT01304758 ExAblate Transcranial MR Guided Focused Ultrasound in the Treatment of Essential Tremor https://ClinicalTrials.gov/show/NCT01304758 Completed InSightec 2012-10-31
NCT02052271 Experimental Therapeutics in Essential Tremor Using Cerebellar Transcranial Direct Current Stimulation https://ClinicalTrials.gov/show/NCT02052271 Completed Institut National de la Santé Et de la Recherche Médicale, France 2018-03-27
NCT02046863 Pilot Study for Automated Deep Brain Stimulation Programming https://ClinicalTrials.gov/show/NCT02046863 Completed Great Lakes NeuroTechnologies Inc. 2014-08-31
NCT03778060 Long-Term Transcutaneous Stimulation and Essential Tremor: A PET Study https://ClinicalTrials.gov/show/NCT03778060 Recruiting Mayo Clinic 2020-12-31
NCT01978080 Continuous Tremor Assessment During Daily Activities https://ClinicalTrials.gov/show/NCT01978080 Completed Great Lakes NeuroTechnologies Inc. 2014-12-31
NCT01961297 Voice Tremor in Spasmodic Dysphonia: Central Mechanisms and Treatment Response https://ClinicalTrials.gov/show/NCT01961297 Completed Icahn School of Medicine at Mount Sinai 2017-06-30
NCT01932463 ExAblate (Magnetic Resonance-guided Focused Ultrasound Surgery) for Treatment of Tremor https://ClinicalTrials.gov/show/NCT01932463 Completed InSightec 2012-12-31
NCT04299087 Repetitive Transcranial Magnetic Stimulation (rTMS) for Dystonia and Tremor https://ClinicalTrials.gov/show/NCT04299087 Recruiting University of Florida 2026-02-28
NCT01827904 ExAblate Transcranial MR Guided Focused Ultrasound for the Treatment of Essential Tremors https://ClinicalTrials.gov/show/NCT01827904 Active, not recruiting InSightec 2021-12-31
NCT01731145 Assessment of Tremor Using SNUMAP Motion Sensing System https://ClinicalTrials.gov/show/NCT01731145 Completed Seoul National University Hospital 2015-02-28
NCT01579435 Experimental Therapeutics in Essential Tremor Using Transcranial Direct Current Stimulation https://ClinicalTrials.gov/show/NCT01579435 Completed Institut National de la Santé Et de la Recherche Médicale, France 2013-04-30
NCT01468948 Octanoic Acid for Essential Tremor https://ClinicalTrials.gov/show/NCT01468948 Completed National Institutes of Health Clinical Center (CC) 2012-07-18
NCT01438710 Switching Study of Kidney Transplant Patients With Tremor to LCP-Tacro (STRATO) https://ClinicalTrials.gov/show/NCT01438710 Completed Veloxis Pharmaceuticals 2012-08-31
NCT03152136 A Pilot Study of the Cala ONE Device for Essential Tremor https://ClinicalTrials.gov/show/NCT03152136 Completed Cala Health, Inc. 2018-03-08
NCT01334814 Chronic Versus Intermittent Deep Brain Stimulation for Essential Tremor https://ClinicalTrials.gov/show/NCT01334814 Completed Mayo Clinic 2005-09-30
NCT01332695 A Pilot Efficacy and Safety Study of ST101 in Essential Tremor https://ClinicalTrials.gov/show/NCT01332695 Completed Sonexa Therapeutics, Inc. 2011-12-31
NCT04428567 Treadmill Training in Fragile X-associated Tremor/Ataxia Syndrome https://ClinicalTrials.gov/show/NCT04428567 Recruiting Rush University Medical Center 2021-07-30
NCT04279912 MR-Guided Focused Ultrasound (MRgFUS) for the Management of Tremor in Patients With Multiple Sclerosis https://ClinicalTrials.gov/show/NCT04279912 Recruiting Sunnybrook Health Sciences Centre 2021-03-31
NCT04260971 Cyclic Deep Brain Stimulation in Essential Tremor https://ClinicalTrials.gov/show/NCT04260971 Recruiting King’s College Hospital NHS Trust 2021-03-01
NCT04074031 Transcranial Ultrasound Therapy of Essential Tremor https://ClinicalTrials.gov/show/NCT04074031 Recruiting Assistance Publique - Hôpitaux de Paris 2023-05-31
NCT00223743 A Safety/Efficacy Trial of Zonisamide for Essential Tremor https://ClinicalTrials.gov/show/NCT00223743 Completed VA Greater Los Angeles Healthcare System 2008-09-30
NCT04065022 The Trans-cutaneous Effects on Physiological Tremor Entertainment During tACS https://ClinicalTrials.gov/show/NCT04065022 Completed KU Leuven 2018-01-16
NCT03952117 Transcranial Direct Current Stimulation of the Motor Cortex in Essential Tremor https://ClinicalTrials.gov/show/NCT03952117 Recruiting Lebanese American University 2021-06-30
NCT03832712 The Swedish Essential Tremor (SWEET) Trial https://ClinicalTrials.gov/show/NCT03832712 Recruiting Karolinska Institutet 2024-01-30
NCT03875404 Next-Generation Pre-Operative Targeting for Thalamic DBS in the Treatment of Tremor https://ClinicalTrials.gov/show/NCT03875404 Recruiting Mayo Clinic 2020-12-31
NCT03805750 Trial of Cannabis for Essential Tremor https://ClinicalTrials.gov/show/NCT03805750 Recruiting University of California, San Diego 2020-09-30
NCT03795935 Relief From Side Effects: Clinical Use of Electrodes With Direction https://ClinicalTrials.gov/show/NCT03795935 Recruiting University of British Columbia 2019-07-01
NCT03780426 tSMS in Essential Tremor https://ClinicalTrials.gov/show/NCT03780426 Recruiting Fundación de investigación HM 2019-03-31
NCT03688685 A Clinical Study to Evaluate CAD-1883 in Essential Tremor https://ClinicalTrials.gov/show/NCT03688685 Completed Cadent Therapeutics 2019-09-10
NCT03597100 Prospective Study for Symptomatic Relief of ET With Cala Therapy https://ClinicalTrials.gov/show/NCT03597100 Completed Cala Health, Inc. 2019-05-29
NCT03560622 Functional Neuroimaging Feedback for Focused Ultrasound Thalamotomy https://ClinicalTrials.gov/show/NCT03560622 Active, not recruiting Ohio State University 2019-12-31
NCT03530033 Lidocaine Reduces Muscle Tremor is Beneficial for Intraoperative Recurrent Laryngeal Nerve Monitoring https://ClinicalTrials.gov/show/NCT03530033 Recruiting Fujian Medical University 2018-10-31
NCT03465761 Staged Bilateral Exablate Treatment of Medication Refractory Essential Tremor https://ClinicalTrials.gov/show/NCT03465761 Recruiting InSightec 2021-12-01
NCT01223144 Decision-making and Emotion Recognition in Essential Tremor https://ClinicalTrials.gov/show/NCT01223144 Completed University Hospital, Bordeaux 2011-12-31
NCT01093027 Electrophysiological Study of the Effects of Limb Cooling on Essential Tremor https://ClinicalTrials.gov/show/NCT01093027 Completed Mayo Clinic 2011-12-31
NCT01169324 Effect of Deep Brain Stimulation (DBS) on Sleep Architecture in Patients With Movement Disorders https://ClinicalTrials.gov/show/NCT01169324 Completed University of Alabama at Birmingham 2015-12-11
NCT01018485 The Efficacy of Botulinum Toxin in Disabling Multiple Sclerosis (MS) Tremor https://ClinicalTrials.gov/show/NCT01018485 Completed Melbourne Health 2010-02-28
NCT00998660 RECHARGE Sub-Study to the Implantable Systems Performance Registry (ISPR) https://ClinicalTrials.gov/show/NCT00998660 Completed MedtronicNeuro 2013-07-31
NCT00848172 Double-Blind, Placebo Controlled Pilot Study of Octanoic Acid in Essential Tremor https://ClinicalTrials.gov/show/NCT00848172 Completed National Institutes of Health Clinical Center (CC) 2010-11-30
NCT03935581 Safety and Feasibility of ExAblate Neuro System to Perform Auto-Focusing Echo Imaging in Patients With Essential Tremor https://ClinicalTrials.gov/show/NCT03935581 Recruiting InSightec 2020-12-31
NCT03760406 Optimization of VIM Targeting in Essential Tremor Surgery https://ClinicalTrials.gov/show/NCT03760406 Recruiting University Hospital, Bordeaux 2021-03-31
NCT03487705 Essential Tremor in Children and Adolescent https://ClinicalTrials.gov/show/NCT03487705 Recruiting University Hospital, Montpellier 2020-07-01
NCT02037217 ExAblate Transcranial MR Guided Focused Ultrasound in the Treatment of Essential Tremor https://ClinicalTrials.gov/show/NCT02037217 Completed InSightec 2014-01-31
NCT01250067 Motor-related Cortical Potential in Patients With Essential Tremor https://ClinicalTrials.gov/show/NCT01250067 Completed China Medical University Hospital NA
NCT03101241 A Phase 2 RCT Study of CX-8998 for Essential Tremor https://ClinicalTrials.gov/show/NCT03101241 Completed Jazz Pharmaceuticals 2019-05-28
NCT02711995 Essential Voice Tremor: A Study of Botulinum Toxin Treatment and Injection Augmentation https://ClinicalTrials.gov/show/NCT02711995 Completed Weill Medical College of Cornell University 2016-09-29
NCT00646451 Pregabalin in the Treatment of Essential Tremor https://ClinicalTrials.gov/show/NCT00646451 Completed Baylor College of Medicine 2008-12-31
NCT00598078 Multiple-dose,Double-blind,Placebo-controlled Study of Sodium Oxybate in Patients With Essential Tremor https://ClinicalTrials.gov/show/NCT00598078 Completed Jazz Pharmaceuticals 2008-08-31
NCT00584948 Memantine Treatment in Fragile X-Associated Tremor/Ataxia Syndrome https://ClinicalTrials.gov/show/NCT00584948 Completed University of California, Davis 2012-09-30
NCT00584376 Pregabalin (Lyrica) for the Treatment of Essential Tremor https://ClinicalTrials.gov/show/NCT00584376 Completed University of South Florida 2010-11-30
NCT00524056 A Proof of Concept Study of the Effectiveness of Carisbamate in the Treatment of Essential Tremor https://ClinicalTrials.gov/show/NCT00524056 Completed SK Life Science, Inc. 2008-03-31
NCT00468078 Efficacy and Safety of F-18 FPCIT PET in Parkinson’s Disease and Essential Tremor Patients https://ClinicalTrials.gov/show/NCT00468078 Completed Asan Medical Center 2007-09-30
NCT00439699 A Pilot Clinical Trial Of Memantine for Essential Tremor https://ClinicalTrials.gov/show/NCT00439699 Completed VA Greater Los Angeles Healthcare System 2008-12-31
NCT00236496 A Comparison of the Efficacy and Safety of Topiramate Versus Placebo in Treating Tremor of Unknown Cause. https://ClinicalTrials.gov/show/NCT00236496 Completed Johnson & Johnson Pharmaceutical Research & Development, L.L.C. NA
NCT00102596 Clinical Trial Characterizing the Bioavailability of 1-Octanol in Adults With Ethanol-responsive Essential Tremor https://ClinicalTrials.gov/show/NCT00102596 Completed National Institutes of Health Clinical Center (CC) 2009-09-30
NCT00080366 Octanol to Treat Essential Tremor https://ClinicalTrials.gov/show/NCT00080366 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001986 1-Octanol to Treat Essential Tremor https://ClinicalTrials.gov/show/NCT00001986 Completed National Institutes of Health Clinical Center (CC) NA
NCT00016679 1-Octanol to Treat Essential Tremor https://ClinicalTrials.gov/show/NCT00016679 Completed National Institutes of Health Clinical Center (CC) NA
NCT00620165 Efficacy of Levetiracetam in Essential Tremor https://ClinicalTrials.gov/show/NCT00620165 Completed Southern California Institute for Research and Education 2008-03-31
NCT00018564 Novel Therapies for Essential Tremor https://ClinicalTrials.gov/show/NCT00018564 Completed VA Office of Research and Development NA
NCT00001925 Effect of Alcohol on Tremors https://ClinicalTrials.gov/show/NCT00001925 Completed National Institutes of Health Clinical Center (CC) NA

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT04198246 Chinese ET Registry (CETR) https://ClinicalTrials.gov/show/NCT04198246 Recruiting Xiangya Hospital of Central South University 2028-12-31
NCT03300193 The Effect of Lesion Characteristics in MRgFUS on Tremor in Essential Tremor and Parkinson’s Disease https://ClinicalTrials.gov/show/NCT03300193 Completed Rambam Health Care Campus 2017-05-31
NCT03041714 Neurophysiologic Study of Patient With Essential Tremor and Dystonic Tremor https://ClinicalTrials.gov/show/NCT03041714 Completed National Institutes of Health Clinical Center (CC) 2018-03-22
NCT03027310 Clinical and Physiological Studies of Tremor Syndromes https://ClinicalTrials.gov/show/NCT03027310 Recruiting National Institutes of Health Clinical Center (CC) 2022-01-01
NCT02936531 Brain Network Activation and Gait and Posture in FXTAS https://ClinicalTrials.gov/show/NCT02936531 Recruiting Sheba Medical Center 2018-10-31
NCT02762682 A Study of Vitamin B12 Status in Children With Infantile Tremor Syndrome and Pre Infantile Tremor Syndrome https://ClinicalTrials.gov/show/NCT02762682 Completed Postgraduate Institute of Medical Education and Research 2016-12-31
NCT02712515 The Motor Network in Essential Tremor: Mechanisms of Therapy https://ClinicalTrials.gov/show/NCT02712515 Recruiting University of Florida 2021-03-31
NCT02569021 Battery-preserving Stimulation Patterns for Deep Brain Stimulation https://ClinicalTrials.gov/show/NCT02569021 Completed University of Florida 2016-04-30
NCT01734122 Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor https://ClinicalTrials.gov/show/NCT01734122 Recruiting Vanderbilt University Medical Center 2023-02-28
NCT02523807 Tremor Monitoring Device https://ClinicalTrials.gov/show/NCT02523807 Completed Rambam Health Care Campus 2017-10-30
NCT02132052 Defining Phenotypes of Movement Disorders :Parkinson’s Plus Disorders (PD), Essential Tremor (ET), Cortical Basal Degeneration (CBD), Multiple Systems Atrophy (MSA), Magnetoencephalography. https://ClinicalTrials.gov/show/NCT02132052 Active, not recruiting University of Colorado, Denver 2020-12-31
NCT02071446 Local Fields Potentials Recorded From Deep Brain Stimulating Electrodes https://ClinicalTrials.gov/show/NCT02071446 Completed University of Colorado, Denver 2017-11-29
NCT02067702 Limb Cooling in Essential Tremor https://ClinicalTrials.gov/show/NCT02067702 Completed University of Florida 2016-08-31
NCT01952678 Compare Rates of Agreement Between Clinical Diagnosis and Visual Assessment of DaTscanâ„¢ Images in Non-Caucasian and Caucasian Subjects With Parkinson’s Disease (PD) or Essential Tremor (ET) https://ClinicalTrials.gov/show/NCT01952678 Completed GE Healthcare 2016-05-31
NCT01602042 Adaptive Portable Essential Tremor Monitor https://ClinicalTrials.gov/show/NCT01602042 Completed Great Lakes NeuroTechnologies Inc. 2012-11-30
NCT01547481 MRI Study of Brain Activity in Healthy Adults and Individuals With Parkinsonism and Rapid Eye Movement Disorder. https://ClinicalTrials.gov/show/NCT01547481 Completed University of Alabama at Birmingham 2015-12-31
NCT03992625 Clinical Outcomes for Deep Brain Stimulation https://ClinicalTrials.gov/show/NCT03992625 Recruiting Washington University School of Medicine 2030-01-01
NCT03884231 MRI Study of Infinity DBS System https://ClinicalTrials.gov/show/NCT03884231 Recruiting Abbott Medical Devices 2021-04-30
NCT03769961 Ataxia in Essential Tremor: Describing the Differences Between Disease Process and Treatment Effect https://ClinicalTrials.gov/show/NCT03769961 Recruiting Oregon Health and Science University 2020-12-31
NCT03696420 Probabilistic Targeting of the VIM https://ClinicalTrials.gov/show/NCT03696420 Recruiting University Hospital, Bordeaux 2020-11-30
NCT01200966 Ethanol Response in Essential Tremor: Clinical and Neurophysiological Correlates https://ClinicalTrials.gov/show/NCT01200966 Completed National Institutes of Health Clinical Center (CC) NA
NCT00906412 Ventrointermediate Nucleus (VIM DBS) and Working Memory https://ClinicalTrials.gov/show/NCT00906412 Completed Washington University School of Medicine 2013-09-30
NCT03350139 Evaluation of the Predictors of Clinical and Radiological Response to Gamma-Knife Radiosurgery in the Treatment of Intermediate Ventral Nucleus of the Thalamus (VIM) Thalamotomy Tremor. https://ClinicalTrials.gov/show/NCT03350139 Recruiting Assistance Publique Hopitaux De Marseille 2021-10-22
NCT02668835 GADGET-PD Genetic and Digital Diagnosis of Essential Tremor and Parkinson’s Disease Trial https://ClinicalTrials.gov/show/NCT02668835 Completed Scripps Translational Science Institute 2017-02-28
NCT02641366 Electromagnetic Tracking to Measure Tremor https://ClinicalTrials.gov/show/NCT02641366 Completed University of Florida 2016-12-31
NCT04071847 Abbott DBS Registry of Outcomes for Indications Over Time https://ClinicalTrials.gov/show/NCT04071847 Recruiting Abbott Medical Devices 2029-09-30
NCT01534650 Movement Disorder Quantification Algorithm Development https://ClinicalTrials.gov/show/NCT01534650 Completed Great Lakes NeuroTechnologies Inc. 2016-01-31
NCT00596908 123I-ALTROPANE® Reference Image Acquisition in Subjects With Diagnostically Uncertain Tremor https://ClinicalTrials.gov/show/NCT00596908 Completed Alseres Pharmaceuticals, Inc NA
NCT00001667 Genotype/Phenotype Correlation of Movement Disorders and Other Neurological Diseases https://ClinicalTrials.gov/show/NCT00001667 Completed National Institutes of Health Clinical Center (CC) NA
NCT00001324 PET Scan to Study Brain Control of Human Movement https://ClinicalTrials.gov/show/NCT00001324 Completed National Institutes of Health Clinical Center (CC) NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03100474 Global Registry: ExAblate Neuro MR Guided Focused Ultrasound (MRgFUS) of Neurological Disorders: https://ClinicalTrials.gov/show/NCT03100474 Active, not recruiting InSightec 2021-01-31
NCT04288804 A Study to Analyze Symptoms Prevalent in Early PD (Dysphonia, Tremor) https://ClinicalTrials.gov/show/NCT04288804 Recruiting Goalspal LLC 2020-12-26
NCT04032470 Boston Scientific Registry of Deep Brain Stimulation for Treatment of Essential Tremor (ET) https://ClinicalTrials.gov/show/NCT04032470 Recruiting Boston Scientific Corporation 2028-12-31